HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1857198Generated: October 25, 2026
3-Hydroxybenzophenone → {3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanone
https://huagongshe.com/reaction/1857198
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Hydroxybenzophenone | HCID 83050 | — |
| Reactant | 4-Chloro-6,7-dimethoxyquinoline | HCID 459610 | — |
| Product | {3-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}phenylmethanone | HCID 53907205 | 65.3% |
Reaction Steps
A mixture of 4-chloro-6,7-dimethoxyquinoline (112 mg) and commercially available 3-hydroxybenzophenone (297 mg) was stirred at 170° C. for 10 minutes, the reaction mixture was then purified by thin layer chromatography on silica gel eluting with hexane/acetone (2/1) to obtain 126 mg of the title compound (yield: 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06143764 |
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| Source dataset | uspto-grants-2000_11 |
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| ORD ID | ord-a2e9c24a256f4eb3a7ffd7bf2e26bd73 |
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| Source note | uspto-grants-2000_11 |
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