反应详情

6,7-Dimethoxy-4-(4-aminophenoxy)quinoline (53 mg) was dissolved in toluene (5 ml) with heat, 2,4-dichlorophenyl isocyanate (115 mg) was added, and the admixture was refluxed with heat for 20 minutes. The separated crystals were filtered and then washed with toluene to obtain 74 mg of the title compound (yield: 85%).

1. temperaturewith heat
2. temperaturethe admixture was refluxed
3. temperaturewith heat for 20 minutes
4. filtrationThe separated crystals were filtered
5. washwashed with toluene