HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 22129431, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-(Isoxazol-3-yl)-4-methylsulfonyl-2-methylbenzoic acid | HCID 22129430 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 22129431 | HCID 22129431 | — |
Reaction Steps
To 0.55 g of 3-(isoxazol-3-yl)-4-methylsulfonyl-2-methylbenzoic acid were added 10 ml of benzene, then 0.17 ml of thionyl chloride and a drop of triethylamine to heat at reflux for 2 hours. The reaction solution was cooled down. The solvent was distilled out under reduced pressure to give 3-(isoxazol-3-yl)-4-methylsulfonyl-2-methylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06147031 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-b1030ab30f9d44afa1bb49b097ab270c |
| Source note | uspto-grants-2000_11 |