HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → N-(4-fluorophenyl)-N'-2-butanesulfonylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Fluorophenyl isocyanate | HCID 70955 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Butane-2-sulfonamide | HCID 20482438 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-(4-fluorophenyl)-N'-2-butanesulfonylurea | HCID 22131305 | — |
Reaction Steps
The general method of procedure B was followed with 2-butanesulfonamide (6.85 g), sodium methoxide (2.7 g), methanol (250 ml), and 4-fluorophenyl isocyanate (6.8 g) except 1N HCl was added to provide the free urea. The solid was recrystallized from benzene to provide 5.2 g of white powder with a melting point of 136-138° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06147115 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-18ccd7195a9e4295aa05e2902a86d254 |
| Source note | uspto-grants-2000_11 |