Hydrochloric Acid → HCID 15484973, compound

HRID 1857579Notes

Reaction equation

HRID 1857579 reaction equation
[CH2:1]([S:6]([NH2:9])(=[O:8])=[O:7])[CH2:2][CH2:3][CH2:4][CH3:5].[OH-].[Na+].[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1.Cl>O.CC(C)=O>[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19][C:20]([NH:9][S:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])(=[O:8])=[O:7])=[O:21])=[CH:15][CH:14]=1

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 76934-Chlorophenyl IsocyanateHCID 14798Sodium HydroxideHCID 109206961-Pentanesulfonamide

Product 1

HCID 15484973HCID 15484973, compoundYield 73.5%

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

The general method of procedure A was followed with 1-pentanesulfonamide (10 g), acetone (200 ml), 1N NaOH (66 ml) and 4-chlorophenyl isocyanate (9.6 g). 1N HCl (66 ml) was used to acidify the solution. Additional water was added and after standing overnight the solid was isolated and dried to provide 14 g of product.

Workup

  1. customthe solid was isolated
  2. customdried

Sources & evidence

ORD record
ord-c6a234f2f3b64409a467564d5fca5d9d
Source dataset
uspto-grants-2000_11
Patent number
US06147115

Reaction notes

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