Hydrochloric Acid → HCID 70274422, compound

HRID 1857580Notes

Reaction equation

HRID 1857580 reaction equation
[CH3:1][CH2:2][CH:3]([S:6]([NH2:9])(=[O:8])=[O:7])[CH2:4][CH3:5].[OH-].[Na+].[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([N:19]=[C:20]=[O:21])=[CH:15][CH:14]=1.Cl>CC(C)=O.O>[Cl:12][C:13]1[CH:18]=[CH:17][C:16]([NH:19][C:20]([NH:9][S:6]([CH:3]([CH2:4][CH3:5])[CH2:2][CH3:1])(=[O:8])=[O:7])=[O:21])=[CH:15][CH:14]=1

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 76934-Chlorophenyl IsocyanateHCID 14798Sodium HydroxideHCID 22131302139669-27-5

Product 1

HCID 70274422HCID 70274422, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolvent3×HCID 962WaterSolvent

Procedure

The general method of procedure A was followed with 3-pentanesulfonamide (10 g), acetone (300 ml), 1N sodium hydroxide (56 ml), and 4-chlorophenyl isocyanate (9.6 g) dissolved in 70 ml of acetone. After two hours of stirring, 1N HCl (66 ml) was added followed by more water. The acetone was stripped off, and the resulting solid collected, to give, after drying at 65° C. under vacuum, 13.1 g of product.

Workup

  1. customthe resulting solid collected
  2. customto give
  3. dry with materialafter drying at 65° C. under vacuum, 13.1 g of product

Sources & evidence

ORD record
ord-6a094da47c8342ec8ab7da94d80b7250
Source dataset
uspto-grants-2000_11
Patent number
US06147115

Reaction notes

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