Dicyandiamide → HCID 9927584, compound

HRID 1857940Notes

Reaction equation

HRID 1857940 reaction equation
[C:1]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]2[CH2:11][CH:10]([C:12]#[N:13])[CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:20]([N:22]=[C:23]([NH2:25])[NH2:24])#[N:21].[OH-].[K+]>COCCO.O>[C:1]1([CH:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:8]2[CH2:11][CH:10]([C:12]3[N:24]=[C:23]([NH2:25])[N:22]=[C:20]([NH2:21])[N:13]=3)[CH2:9]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

6

Reactant 3

HCID 10005DicyandiamideHCID 14797Potassium HydroxideHCID 27792901-(Diphenylmethyl)azetidine-3-carbonitrile

Product 1

HCID 9927584HCID 9927584, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 80192-MethoxyethanolSolvent

Procedure

A solution of 1-(diphenylmethyl)-3-azetidinecarbonitrile (500 mg, 2.01 mmol), dicyandiamide (220 mg, 2.62 mmol) and KOH (34 mg, 0.604 mmol) in 2-methoxyethanol (10 mL) was heated at reflux for 4 hours, diluted with water, and cooled to room temperature. The precipitate was rinsed with water and dried under vacuum to provide the title compound.

Workup

  1. temperatureat reflux for 4 hours
  2. washThe precipitate was rinsed with water
  3. customdried under vacuum

Sources & evidence

ORD record
ord-3e24e78bd94f4eb29b322f54245185d6
Source dataset
uspto-grants-2000_11
Patent number
US06150362

Reaction notes

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