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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1857954Generated: November 3, 2026

Piperidine → HCID 178517788, compound

https://huagongshe.com/reaction/1857954

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
ReactantHCID 178517787HCID 178517787—
ProductHCID 178517788HCID 178517788—

Reaction Steps

The title compound was prepared from 7-chloro-4-hydroxy-2-trifluoromethylquinazoline (2.0 g, 8.0 mmol), as described in Example 43 (but using piperidine in place of N,N-dimethylamine) to provide the desired compound in a 96% (2.5 g) yield; m.p. 268-271° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06150372
Source datasetuspto-grants-2000_11
ORD IDord-60143bc82bbb44519f22f31dc314f317
Source noteuspto-grants-2000_11