Methyl 4-ethynylbenzoate → HCID 54554152, compound

HRID 1858051Notes

Reaction equation

HRID 1858051 reaction equation
I/[CH:2]=[CH:3]/[C:4]1[CH:9]=[CH:8][C:7]([CH3:10])=[CH:6][C:5]=1[C:11]1[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=1.[C:18]([C:20]1[CH:29]=[CH:28][C:23]([C:24]([O:26]C)=[O:25])=[CH:22][CH:21]=1)#[CH:19]>>[CH3:10][C:7]1[CH:8]=[CH:9][C:4]([CH:3]=[CH:2][C:19]#[C:18][C:20]2[CH:29]=[CH:28][C:23]([C:24]([OH:26])=[O:25])=[CH:22][CH:21]=2)=[C:5]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)[CH:6]=1

Participants

3

Reactant 2

HCID 640163Methyl 4-ethynylbenzoateHCID 22125814HCID 22125814, compound

Product 1

HCID 54554152HCID 54554152, compoundYield 28.4%

Procedure

In a similar manner to that of Example 1(e), by reaction of 3.69 g (11.0 mmol) of 2-((E)-2-iodovinyl)-5,4'-dimethylbiphenyl obtained in Example 13(f) with 1.60 g (10.0 mmol) of methyl 4-ethynylbenzoate, 1.00 g (27%) of the expected compound is obtained in the form of a white powder with a melting point of 123-125° C.

Sources & evidence

ORD record
ord-af1d17c3553d425f88529f2690609d8d
Source dataset
uspto-grants-2000_11
Patent number
US06150413

Reaction notes

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