Methyl 2-amino-4-chloro-5-iodobenzoate → Methyl 4-chloro-2-(2-(5-chlorothiophen-2-yl)acetamido)-5-iodobenzoate

Participants

Role	Name	HCID	Charge
Reactant	Methyl 2-amino-4-chloro-5-iodobenzoate	HCID 10852539	—
Reactant	(5-Chlorothiophen-2-yl)acetyl chloride	HCID 15740376	—
Product	Methyl 4-chloro-2-(2-(5-chlorothiophen-2-yl)acetamido)-5-iodobenzoate	HCID 54342187	74.1%

Reaction Steps

Prepared essentially as described in EXAMPLE 1, Step A from 5.0 g 2-amino-4-chloro-5-iodobenzoic acid methyl ester and 2.8 g (5-chlorothiophen-2-yl)acetyl chloride (also prepared essentially as described in EXAMPLE 1) to give the title compound (5.0 g).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06150522
Source dataset	uspto-grants-2000_11
ORD ID	ord-c94f2dc00763418abd9246833bf04889
Source note	uspto-grants-2000_11