HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(Tert-butyldiphenylsilyloxy)ethyl]nitrobenzene → 4-[2-(Tert-butyldiphenylsilyloxy)ethyl]phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(Tert-butyldiphenylsilyloxy)ethyl]nitrobenzene | HCID 22125112 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-[2-(Tert-butyldiphenylsilyloxy)ethyl]phenylamine | HCID 22124994 | 94.9% |
Reaction Steps
A solution of 6.5 g (16 mmol) 4-[2-(tert-butyldiphenylsilyloxy)ethyl]nitrobenzene in methanol (30 ml) containing 750 mg of 10% palladium on carbon was hydrogenated at room temperature and atmospheric pressure for 2 hours. The catalyst was removed by filtration and the solvent evaporated to give 5.7 g of 4-[2-(tert-butyldiphenylsilyloxy)ethyl]phenylamine as a colorless liquid. [Mass spectrum (ESI) MH+ =376].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06150373 |
| Source dataset | uspto-grants-2000_11 |
| ORD ID | ord-d0bb3e578c134171811bbc8dfd49acb8 |
| Source note | uspto-grants-2000_11 |