Methanol → Avosentan

HRID 185879Notes

Reaction equation

HRID 185879 reaction equation
[CH3:35][OH:36].[Cl:2][c:3]1[c:4]([O:26][c:27]2[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]2)[c:5]([NH:15][S:16](=[O:17])(=[O:18])[c:19]2[n:20][cH:21][c:22]([CH3:25])[cH:23][cH:24]2)[n:6][c:7](-[c:9]2[cH:10][cH:11][n:12][cH:13][cH:14]2)[n:8]1.[Na:1]>>[c:3]1([O:36][CH3:35])[c:4]([O:26][c:27]2[c:28]([O:33][CH3:34])[cH:29][cH:30][cH:31][cH:32]2)[c:5]([NH:15][S:16](=[O:17])(=[O:18])[c:19]2[n:20][cH:21][c:22]([CH3:25])[cH:23][cH:24]2)[n:6][c:7](-[c:9]2[cH:10][cH:11][n:12][cH:13][cH:14]2)[n:8]1

Participants

4

Reactant 3

HCID 887MethanolHCID 5360545SodiumHCID 11202530HCID 11202530, compound

Product 1

HCID 9912992Avosentan

Sources & evidence

ORD record
ord-8687f77ee6df4e7f9c674315017ee477
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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