HRID1858917

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[C@@H]1CN(C(=O)OC(C)(C)C)[C@@H](C)CN1

HCID11745988

tert-Butyl (2S,5R)-2,5-dimethylpiperazine-1-carboxylate

C11H22N2O2

HCID15487110

4-Methylisoquinoline-5-sulfonyl chloride

C10H8ClNO2S

PRODUCTS

生成物

结构：Cc1cncc2cccc(S(=O)(=O)N3C[C@@H](C)NC[C@@H]3C)c12.Cl.Cl

HCID70272419

未命名化合物

收率 82.8%

PROCEDURE

实验过程

Using 0.34 g of trans-1-(tert-butoxycarbonyl)-2,5-dimethylpiperazine and 0.64 g of 5-chlorosulfonyl-4-methylisoquinoline, the procedure of Example 1 was otherwise repeated to provide 0.43 g of the objective compound (white crystals).