反应详情

Using 0.65 g of 6-fluoro-hexahydro-1H-1,4-diazepine synthesized in accordance with J. Med. Chem., 1990, 33, 142 and 0.72 g of 5-chlorosulfonyl-4-methylisoquinoline, the procedure of Example 1 was otherwise repeated to provide 0.35 g of the objective compound (white crystals).

1. customsynthesized in accordance with J