2-(Chloromethyl)quinoline hydrochloride → HCID 178505743, compound

Participants

Reaction Steps

This compound was prepared from trans 1-[4-(4-fluorophenyl)-1-cyclohexyl]piperazine (2.4 mmole) and 2-chloromethylquinoline hydrochloride (2.4 mmole) by the method described in Example 45 to give the product (82%, mp 160-162° C.). Calc'd for C26H30FN3.0.2H2O: C, 76.70%; H, 7.53%; N, 10.32% Found: C, 76.68%; H, 7.49%; N, 10.32%.

Provenance & Evidence