HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ether hydrochloride → 5,11-Dihydro-5-[2-[N-(4-dimethylaminophenethyl)-N-methylamino]ethyl]dibenzo[b,e][1,4]oxazepine Dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ether hydrochloride | HCID 10953452 | — |
| Reactant | 5,11-dihydro-5-[2-[N-(4-dimethylaminophenethyl)-N-methylamino]ethyl]dibenzo[b,e][1,4]oxazepine | HCID 18625598 | — |
| Product | 5,11-Dihydro-5-[2-[N-(4-dimethylaminophenethyl)-N-methylamino]ethyl]dibenzo[b,e][1,4]oxazepine Dihydrochloride | HCID 18625617 | — |
Reaction Steps
5 ml of 2 M hydrochloric acid/ethyl ether was added to 5,11-dihydro-5-[2-[N-(4-dimethylaminophenethyl)-N-methylamino]ethyl]dibenzo[b,e][1,4]oxazepine (184 mg, 0.46 mmol), and they were stirred for 1 hour. The solvent was evaporated under reduced pressure to obtain the title compound in the form of light green crystals (194 mg, 89%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528504B2 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-83ca36dd695c42d0993c8104b449e95b |
| Source note | uspto-grants-2003_03 |