HCID 5007546, compound → HCID 18626083, compound

HRID 1859664Notes

Reaction equation

HRID 1859664 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9][C:10](=[O:17])[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:4]=1[N+:18]([O-])=O>[Zn]>[NH2:18][C:4]1[CH:5]=[C:6]([NH:9][C:10](=[O:17])[C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:7]=[CH:8][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 1

HCID 5007546HCID 5007546, compound

Product 1

HCID 18626083HCID 18626083, compoundYield 76.4%

Reagents, catalysts & solvents 1

HCID 23994ZincCatalyst

Procedure

Prepared according to the procedure described for Example 9, Step B using N-(4-methoxy-3-nitrophenyl)-benzamide (3.68 g, 13.5 mmol) and zinc dust (20 g) to give the product (2.5 g) after chromatography on silica gel in ethyl acetate/hexane and recrystallization from the same solvent.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a49e96ab52e3417cb58a2eb54bd2cf8d
Source dataset
uspto-grants-2003_03
Patent number
US06528528B2

Reaction notes

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