Sodium Hydroxide → HCID 18625740, compound

Participants

Reaction Steps

In a similar manner to that described in Example 2, ethyl 2-butyl-3-[4-[2-(4′-dimethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionate (1.88 g), which is the product of Reference example 11, was reacted with aqueous sodium hydroxide solution (1N, 6.80 ml) and the reaction mixture was treated to give 2-butyl-3-[4-[2-(4′-dimethoxymethylbiphenyl-4-carbonylamino)ethoxy]phenyl]propionic acid (1.78 g) as a pale brown solid.

Provenance & Evidence