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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859934Generated: October 29, 2026

Sodium Hydroxide → 3-[4-[2-(biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N-ethyl-N-phenylamino)propionic acid

https://huagongshe.com/reaction/1859934

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 3-[4-[2-(biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N-ethyl-N-phenylamino)propionateHCID 18625935—
SolventMethanolHCID 887—
Product3-[4-[2-(biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N-ethyl-N-phenylamino)propionic acidHCID 18625816—

Reaction Steps

Ethyl 3-[4-[2-(biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N-ethyl-N-phenylamino)propionate, which is the product of Example 181, is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-fbec062901c84397ad771effe62df0ac
Source noteuspto-grants-2003_03