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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859937Generated: October 31, 2026

Sodium Hydroxide → 3-[4-[2-(Biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N,N-diethylamino)propionic acid

https://huagongshe.com/reaction/1859937

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 2-(N,N-diethylamino)-3-[4-[2-(4-phenylbenzoylamino)ethoxy]phenyl]propionateHCID 18625914—
SolventMethanolHCID 887—
Product3-[4-[2-(Biphenyl-4-carbonylamino)ethoxy]phenyl]-2-(N,N-diethylamino)propionic acidHCID 18625992—

Reaction Steps

Ethyl 2-(N,N-diethylamino)-3-[4-[2-(4-phenylbenzoylamino)ethoxy]phenyl]-propionate, which is the product of Example 189, is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-d374ad7343cb41d4a5381b401a58d96b
Source noteuspto-grants-2003_03