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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859938Generated: October 31, 2026

Sodium Hydroxide → 3-[4-[2-(4-Pyridine-2-ylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionic acid

https://huagongshe.com/reaction/1859938

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantEthyl 3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionateHCID 18626034—
SolventMethanolHCID 887—
Product3-[4-[2-(4-Pyridine-2-ylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionic acidHCID 18625805—

Reaction Steps

Ethyl 3-[4-[2-(4-pyridine-2-ylbenzoylamino)ethoxy]phenyl]-2-(pyrrole-1-yl)propionate, which is the product of Example 191, is hydrolyzed by sodium hydroxide in methanol to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-51fbdc736a054ccf88dde14b0161de54
Source noteuspto-grants-2003_03