Diethyl 2-(4-benzyloxybenzyl)-2-(4-isopropylphenoxy)malonate → Diethyl 2-(4-hydroxyphenyl)-2-(4-isopropylphenoxy)malonate

Participants

Reaction Steps

In a similar manner to that described in Reference example 1(d), a reaction was carried out using diethyl 2-(4-benzyloxybenzyl)-2-(4-isopropylphenoxy)malonate (32.3 g), which is the product of Reference example 5(b), and palladium on carbon (5%, 2.00 g) and the reaction mixture was treated to afford the desired compound (25.2 g) as a syrup.

Provenance & Evidence