p-Toluenesulfonic acid monohydrate → HCID 18625717, compound

Participants

Reaction Steps

In a similar manner to that described in Reference example 3(f), a reaction was carried out using ethyl 2-(4-isopropylphenoxy)-3-[4-[2-(tetrahydropyran-2-yloxy)ethoxy]phenyl]propionate (20.6 g), which is the product of Reference example 5(e), and p-toluenesulfonic acid monohydrate (7.85 g) and the reaction mixture was treated to afford the desired compound (16.2 g) as a syrup.

Provenance & Evidence