HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → Ethyl 2-butyl-3-[4-(2-methanesulfonyloxyethoxy)phenyl]propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | Ethyl 2-butyl-3-[4-(2-hydroxyethoxy)phenyl]propionate | HCID 18625693 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | Ethyl 2-butyl-3-[4-(2-methanesulfonyloxyethoxy)phenyl]propionate | HCID 18625769 | — |
Reaction Steps
In a similar manner to that described in Reference example 3(g), a reaction was carried out using ethyl 2-butyl-3-[4-(2-hydroxyethoxy)phenyl]propionate (1.44 g), which is the product of Reference example 6(e), triethylamine (2.04 ml) and methanesulfonyl chloride (0.76 ml) and the reaction mixture was treated to afford the desired compound (1.65 g) as a syrup.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-0528bfaa25d4464db8d6cb6101bba95a |
| Source note | uspto-grants-2003_03 |