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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1859977Generated: October 31, 2026

Diethyl methylmalonate → HCID 18625691, compound

https://huagongshe.com/reaction/1859977

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl methylmalonateHCID 11857—
Reactant(3-Bromopropyl)benzeneHCID 12503—
ReactantSodium hydrideHCID 24758—
ProductHCID 18625691HCID 1862569179.3%

Reaction Steps

In a similar manner to that described in Reference example 2(a), a reaction was carried out using diethyl 2-methylmalonate (3.48 g), 3-phenylpropyl bromide (3.98 g) and sodium hydride (55% suspension in oil, 0.96 g) and the reaction mixture was treated to afford the desired compound (4.63 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-648244b233894a03849f93b1c2f85088
Source noteuspto-grants-2003_03