p-Toluenesulfonic acid monohydrate → HCID 18625707, compound

Participants

Reaction Steps

In a similar manner to that described in Reference example 3(f), a reaction was carried out using ethyl 2-methyl-2-(3-phenylpropyl)-3-[4-[2-(tetrahydropyran-2-yloxy)ethoxy]phenyl]propionate (1.64 g), which is the product of Reference example 7(e), and p-toluenesulfonic acid monohydrate (0.68 g) and the reaction mixture was treated to afford the desired compound (0.95 g) as a syrup.

Provenance & Evidence