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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860004Generated: October 29, 2026

Methanesulfonyl chloride → HCID 18625741, compound

https://huagongshe.com/reaction/1860004

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanesulfonyl chlorideHCID 31297—
ReactantEthyl 2-butyl-3-[4-(2-hydroxyethoxy)phenyl]-2-methylpropionateHCID 18625749—
SolventTriethylamineHCID 8471—
ProductHCID 18625741HCID 18625741—

Reaction Steps

In a similar manner to that described in Reference example 3(g), a reaction was carried out using ethyl 2-butyl-3-[4-(2-hydroxyethoxy)phenyl]-2-methylpropionate (2.73 g), which is the product of Reference example 10(d), triethylamine (1.85 ml) and methanesulfonyl chloride (0.75 ml) and the reaction mixture was treated to afford the desired compound (3.17 g) as a syrup.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-8b7a9a21ea714a6baa3d72b27e66a08e
Source noteuspto-grants-2003_03