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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860020Generated: November 1, 2026

Sodium Hydroxide → 4-(2-hydroxyphenyl)benzoic Acid

https://huagongshe.com/reaction/1860020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2-(4-Methoxycarbonylphenyl)phenolHCID 4564856—
Product4-(2-hydroxyphenyl)benzoic AcidHCID 1065624492.9%

Reaction Steps

In a similar manner to that described in Example 2, a reaction was carried out using methyl 2′-hydroxybiphenyl-4-carboxylate (498 mg) and aqueous sodium hydroxide (1N, 4.81 ml) and the reaction mixture was treated to afford the title compound (434 mg) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-340d1ef9824643168ccac76c4eb8a5ab
Source noteuspto-grants-2003_03