HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 6-[(Propan-2-yl)oxy]pyridine-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Methylethyl 6-(1-methylethoxy)-3-pyridinecarboxylate | HCID 18625853 | — |
| Product | 6-[(Propan-2-yl)oxy]pyridine-3-carboxylic acid | HCID 18625738 | 100.5% |
Reaction Steps
In a similar manner to that described in Example 2, a reaction was carried out using isopropyl 6-isopropoxynicotinate (130 mg), which is the product of Reference example 18(a) and aqueous sodium hydroxide solution (1N, 0.87 ml) and the reaction mixture was treated to afford the title compound (106 mg) as crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-831b9ce2d6f041a8830776380c06becd |
| Source note | uspto-grants-2003_03 |