Methanesulfonyl chloride → HCID 18625784, compound

HRID 1860027Notes

Reaction equation

HRID 1860027 reaction equation
[CH2:1]([CH:5]([CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][OH:22])=[CH:14][CH:13]=1)[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH2:2][CH2:3][CH3:4].[CH3:23][S:24](Cl)(=[O:26])=[O:25]>C(N(CC)CC)C>[CH2:1]([CH:5]([CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH2:19][CH2:20][CH2:21][O:22][S:24]([CH3:23])(=[O:26])=[O:25])=[CH:14][CH:13]=1)[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 18625878HCID 18625878, compound

Product 1

HCID 18625784HCID 18625784, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In a similar manner to that described in Reference example 3(g), a reaction was carried out using ethyl 2-butyl-3-[4-(3-hydroxypropoxy)phenyl]propionate (3.02 g), triethylamine (2.05 ml) and methanesulfonyl chloride (0.83 ml) and the reaction mixture was treated to afford the desired compound (3.49 g) as a colorless oil.

Workup

  1. additionthe reaction mixture was treated

Sources & evidence

ORD record
ord-ed446cf7c052478fa96fc6be956fbc29
Source dataset
uspto-grants-2003_03
Patent number
US06528525B1

Reaction notes

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