HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 3-(4-Benzyloxyphenyl)-2-propylpropionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Diethyl 2-(4-benzyloxybenzyl)-2-propylmalonate | HCID 18625701 | — |
| Product | 3-(4-Benzyloxyphenyl)-2-propylpropionic acid | HCID 18625990 | 53.7% |
Reaction Steps
In a similar manner to that described in Reference example 2(b), a reaction was carried out using diethyl 2-(4-benzyloxybenzyl)-2-propylmalonate (9.85 g), which is the product of Reference example 23(a), and potassium hydroxide (5.25 g) and the reaction mixture was treated to afford the desired compound (3.96 g) as brown crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06528525B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-3f1237843b184b37b9928155e7c0cbe1 |
| Source note | uspto-grants-2003_03 |