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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860032Generated: October 31, 2026

Potassium Hydroxide → 3-(4-Benzyloxyphenyl)-2-propylpropionic acid

https://huagongshe.com/reaction/1860032

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
ReactantDiethyl 2-(4-benzyloxybenzyl)-2-propylmalonateHCID 18625701—
Product3-(4-Benzyloxyphenyl)-2-propylpropionic acidHCID 1862599053.7%

Reaction Steps

In a similar manner to that described in Reference example 2(b), a reaction was carried out using diethyl 2-(4-benzyloxybenzyl)-2-propylmalonate (9.85 g), which is the product of Reference example 23(a), and potassium hydroxide (5.25 g) and the reaction mixture was treated to afford the desired compound (3.96 g) as brown crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-3f1237843b184b37b9928155e7c0cbe1
Source noteuspto-grants-2003_03