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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860036Generated: October 31, 2026

Sodium Hydroxide → 6-(4-Methoxyphenyl)pyridine-3-carboxylic acid

https://huagongshe.com/reaction/1860036

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 18625729HCID 18625729—
Product6-(4-Methoxyphenyl)pyridine-3-carboxylic acidHCID 1862593370.7%

Reaction Steps

In a similar manner to that described in Example 2, a reaction was carried out using methyl 6-(4-methoxyphenyl)nicotinate (3.95 g) and aqueous sodium hydroxide solution (1N, 32.5 ml) and the reaction mixture was treated to afford the title compound (2.63 g) as colorless crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-e70ca072ff05452e8dda5e203b16360c
Source noteuspto-grants-2003_03