Sodium Hydroxide → 2-(5-Nitropyridin-2-yl)benzoic acid

Participants

Reaction Steps

In a similar manner to that described in Example 2, a reaction was carried out using methyl 3-nitropyridine-6-ylbenzoate (545 mg), which is the product of Reference example 32(a), and aqueous sodium hydroxide solution (1N, 3.16 ml) at 90° C. and the reaction mixture was treated to afford the title compound (370 mg) as colorless crystals.

Provenance & Evidence