p-Toluenesulfonic acid monohydrate → HCID 18625829, compound

Participants

Reaction Steps

In a similar manner to that described in Reference example 3(f), a reaction was carried out using ethyl 2-(4-fluorophenoxy)-3-[4-[2-(tetrahydropyran-2-yloxy)ethoxy]-phenyl]propionate (3.75 g), which is the product of Reference example 37(c), and p-toluensulfonic acid monohydrate (2.15 g) and the reaction mixture was treated to afford the desired compound (2.68 g) as a colorless oil.

Provenance & Evidence