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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860077Generated: October 31, 2026

Hydrogen Bromide → HCID 18625758, compound

https://huagongshe.com/reaction/1860077

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrogen BromideHCID 260—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 18626025HCID 18626025—
SolventAcetic AcidHCID 176—
ProductHCID 18625758HCID 1862575890.8%

Reaction Steps

In a similar manner to that described in Reference example 37(b), a reaction was carried out using ethyl 3-(4-benzyloxyphenyl)-2-(4-trifluoromethoxyphenoxy)propionate (4.08 g), which is the product of Reference example 40(a), a solution of hydrogen bromide in acetic acid (25%, 40 ml) and potassium carbonate (1.68 g) and the reaction mixture was treated to afford the desired compound (2.98 g) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06528525B1
Source datasetuspto-grants-2003_03
ORD IDord-4abd936878844e01b2409fe2b5c27cf0
Source noteuspto-grants-2003_03