Pyridine → 7-[2-(toluene-4-sulfonyloxy)ethyl]-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH2:18][CH2:19][OH:20])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:27][c:28]1[cH:29][cH:30][c:31]([S:34](=[O:35])(=[O:36])[Cl:37])[cH:32][cH:33]1.[Cl:38][CH2:39][Cl:40].[cH:21]1[cH:22][cH:23][n:24][cH:25][cH:26]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][c:12]([CH2:18][CH2:19][O:20][S:34]([c:31]3[cH:30][cH:29][c:28]([CH3:27])[cH:33][cH:32]3)(=[O:35])=[O:36])[cH:13][cH:14][c:15]2[CH2:16][CH2:17]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-2f36543bcca7444696ac57d40b7f5719
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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