Quinapril Hydrochloride → Magnesium Chloride

HRID 1860513Notes

Reaction equation

HRID 1860513 reaction equation
[CH3:1][CH2:2][O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[C@H:29]([C:30]([OH:32])=[O:31])[CH2:28][C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[CH2:21]1)=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)=[O:5].[ClH:33].[OH-].[Mg+2:35].[OH-]>O>[CH3:1][CH2:2][O:3][C:4]([C@@H:6]([NH:15][C@H:16]([C:18]([N:20]1[C@H:29]([C:30]([OH:32])=[O:31])[CH2:28][C:27]2[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=2[CH2:21]1)=[O:19])[CH3:17])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:5].[Mg:35].[Cl-:33].[Mg+2:35].[Cl-:33]

Participants

5

Reactant 2

HCID 54891Quinapril HydrochlorideHCID 73981Magnesium Hydroxide

Product 2

HCID 5360315Magnesium ChlorideHCID 9934075HCID 9934075, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

In the liquid mixture, the 10.0 g of quinapril hydrochloride reacted with 1.23 g of magnesium hydroxide to produce 9.47 g of quinapril magnesium plus 1.00 g of magnesium chloride, plus 0.76 g of water. The liquid was then filtered to remove the excess magnesium hydroxide.

Sources & evidence

ORD record
ord-90f108f835ba47348bac29cd97957a92
Source dataset
uspto-grants-2003_03
Patent number
US06531486B1

Reaction notes

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