反应详情

温度

100 °C

Alternatively, 3-nitro-6-(methylsulfonyl)pyridine was prepared by dissolving of 3-nitro-6-(methylthio)pyridine (1 equivalent) and sodium methane sulfinate in DMSO and heating at 100° C. for 2 hours. The reaction was diluted with a large excess of water and extracted with ethyl acetate. The organic layer was concentrated in vacuo to give the desired 3-nitro-6-(methylsulfonyl)pyridine.

1. customAlternatively, 3-nitro-6-(methylsulfonyl)pyridine was prepared
2. extractionextracted with ethyl acetate
3. concentrationThe organic layer was concentrated in vacuo