Sodium Hydroxide → HCID 18624194, compound

HRID 1860629Notes

Reaction equation

HRID 1860629 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:24])[CH:16]([CH3:23])[CH2:17][C:18]([O:20]CC)=[O:19])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+]>C(O)C>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=[O:24])[CH:16]([CH3:23])[CH2:17][C:18]([OH:20])=[O:19])=[CH:11][CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 18624153HCID 18624153, compound

Product 1

HCID 18624194HCID 18624194, compoundYield 97.2%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
23 °C

Procedure

A mixture of the product of STEP 1 (45 g), ethanol (15 mL) and 15% aqueous NaOH (70 mL) was stirred at 23° C. for 30 minutes. The volatiles were removed in vacuo and the residue was acidified to pH=3. The precipitated solid was filtered and dried to give the above product as a white solid (40 g).

Workup

  1. customThe volatiles were removed in vacuo
  2. filtrationThe precipitated solid was filtered
  3. customdried

Sources & evidence

ORD record
ord-094717d363604f79b204fc811b9656fd
Source dataset
uspto-grants-2003_03
Patent number
US06531494B1

Reaction notes

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