反应详情

A mixture of the product of STEP 7 (81.5 mg, 0.2mmol), 10% Pd/C (50 mg, 0.05 mmol), cyclohexene (0.5 ml, 4.9 mmol), and 2-propanol (5 ml) was heated at reflux for 3 h. The reaction was cooled to room temperature, filtered through a short column of Celite®, and washed with 2-propanol. The filtrate was concentrated to give 67.5 mg pale brown oil. The NMR spectra were consistent for the proposed structure.

1. temperaturewas heated
2. temperatureat reflux for 3 h
3. filtrationfiltered through a short column of Celite®
4. washwashed with 2-propanol
5. concentrationThe filtrate was concentrated