Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860797Generated: October 25, 2026

2,3-Dihydrobenzofuran-5-carboxaldehyde → 3-(2,3-Dihydrobenzofuran-5-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one

https://huagongshe.com/reaction/1860797

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-Dihydrobenzofuran-5-carboxaldehydeHCID 735901—
Reactant5-fluoro-1,3-dihydro-2H-indol-2-oneHCID 3731012—
Product3-(2,3-Dihydrobenzofuran-5-ylmethylene)-5-fluoro-1,3-dihydroindol-2-oneHCID 54022737—

Reaction Steps

2,3-Dihydro-5-formylbenzofuran (commercially available) was condensed with 5-fluoro-2-oxindole to give 0.25 g of 3-(2,3-dihydrobenzofuran-5-ylmethylene)-5-fluoro-1,3-dihydroindol-2-one as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-f1f9a4680714459f952981a953394a6f
Source noteuspto-grants-2003_03