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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1860854Generated: October 27, 2026

2-Oxindole-5-carboxylic acid → 3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid

https://huagongshe.com/reaction/1860854

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxindole-5-carboxylic acidHCID 2773318—
Reactant3,5-Diisopropyl-4-methoxybenzaldehydeHCID 10585025—
Product3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acidHCID 53856327—

Reaction Steps

3,5-Diisopropyl-4-methoxybenzaldehyde was condensed with 5-carboxy-2-oxindole to give 0.4 g of 3-(3,5-diisopropyl-4-methoxybenzylidene)-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid as a yellow-orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06531502B1
Source datasetuspto-grants-2003_03
ORD IDord-554214aefda045ef826615efab7a2565
Source noteuspto-grants-2003_03