HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloropyridine-3-sulfonyl chloride → Isobutyl (2-chloropyridin-3-yl)sulfonyl(3-methoxy-5-methylpyrazin-2-yl)carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloropyridine-3-sulfonyl chloride | HCID 10219968 | — |
| Reactant | Isobutyl (3-methoxy-5-methylpyrazin-2-yl)carbamate | HCID 10889995 | — |
| Product | Isobutyl (2-chloropyridin-3-yl)sulfonyl(3-methoxy-5-methylpyrazin-2-yl)carbamate | HCID 11015197 | — |
Reaction Steps
reaction of 2-chloropyridine-3-sulfonyl chloride with isobutyl N-(3-methoxy-5-methylpyrazin-2-yl)carbamate in the presence of an alkali metal hydride in an inert solvent to give 2-chloro-N-isobutoxycarbonyl-N-(3-methoxy-5-methylpyrazin-2-yl)pyridine-3-sulfonamide;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06531605B1 |
| Source dataset | uspto-grants-2003_03 |
| ORD ID | ord-8cfe341ce247446f94cdcccae494d38a |
| Source note | uspto-grants-2003_03 |