Dichloromethane → 4-(Cyclohexylcarbonyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

HRID 186149Notes

Reaction equation

HRID 186149 reaction equation
[CH:14]1([C:20](=[O:21])[Cl:22])[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[CH:23]([N:24]([CH2:25][CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31].[Cl:32][CH2:33][Cl:34].[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:2][CH2:3][N:4]([C:20]([CH:14]2[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]2)=[O:21])[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 75938Cyclohexanecarbonyl chlorideHCID 81531DiisopropylethylamineHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 673324664-(Cyclohexylcarbonyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester

Sources & evidence

ORD record
ord-b024b98ddb1c4dfdb5fa2305e1c28263
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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