2,3,4-Trimethoxybenzaldehyde → 2,3-Bis-(2,3,4-trimethoxy-phenyl)-acrylonitrile

HRID 1861579Notes

Reaction equation

HRID 1861579 reaction equation
[CH3:1][O:2][C:3]1[C:10]([O:11][CH3:12])=[C:9]([O:13][CH3:14])[CH:8]=[CH:7][C:4]=1[CH:5]=O.[CH3:15][O:16][C:17]1[C:22]([O:23][CH3:24])=[C:21]([O:25][CH3:26])[CH:20]=[CH:19][C:18]=1[CH2:27][C:28]#[N:29]>>[CH3:15][O:16][C:17]1[C:22]([O:23][CH3:24])=[C:21]([O:25][CH3:26])[CH:20]=[CH:19][C:18]=1[C:27](=[CH:5][C:4]1[CH:7]=[CH:8][C:9]([O:13][CH3:14])=[C:10]([O:11][CH3:12])[C:3]=1[O:2][CH3:1])[C:28]#[N:29]

Participants

3

Reactant 2

HCID 750062,3,4-TrimethoxybenzaldehydeHCID 1443172,3,4-Trimethoxyphenylacetonitrile

Product 1

HCID 697792082,3-Bis-(2,3,4-trimethoxy-phenyl)-acrylonitrileYield 93.4%

Procedure

Following the Procedure A, the reaction was performed with 1.96 g of 2,3,4-trimethoxybenzaldehyde (10 mmol) and 2.07 g of 2,3,4-trimethoxyphenyl-acetonitrile (10 mmol), affording 2,3-bis-(2,3,4-trimethoxy-phenyl)-acrylonitrile as yellow powder (yield 3.6 g, 93%).

Sources & evidence

ORD record
ord-3ba7e9d8c2a149c0924e0fc391d31320
Source dataset
uspto-grants-2003_03
Patent number
US06534135B1

Reaction notes

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