反应详情

A mixture of 15.9 g. (0.10 mole) of 1-phenyl-5-aminopyrazole and 21.6 g. (0.10 mole) of diethyl ethoxymethylenemalonate was heated at 115-120° in an oil bath for 2 hours. After cooling, the crystalline mass was recrystallized from hot hexane containing 1% of ethanol. Cooling to room temperature and filtering gave 24.8 g. (75%) of off-white crystals, m.p. 96-97° C.

1. additionA mixture of 15.9 g
2. temperatureAfter cooling
3. customthe crystalline mass was recrystallized from hot hexane containing 1% of ethanol
4. filtrationfiltering
5. customgave 24.8 g