1,3-Dibromopropane → 1-(3-Nitrophenyl)cyclobutanecarboxylic acid

HRID 1861930Notes

Reaction equation

HRID 1861930 reaction equation
C([O:5][C:6](=[O:17])[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([N+:14]([O-:16])=[O:15])[CH:9]=1)(C)(C)C.Br[CH2:19][CH2:20][CH2:21]Br>>[N+:14]([C:10]1[CH:9]=[C:8]([C:7]2([C:6]([OH:5])=[O:17])[CH2:21][CH2:20][CH2:19]2)[CH:13]=[CH:12][CH:11]=1)([O-:16])=[O:15]

Participants

3

Reactant 2

HCID 80011,3-DibromopropaneHCID 18321636HCID 18321636, compound

Product 1

HCID 186220211-(3-Nitrophenyl)cyclobutanecarboxylic acid

Procedure

Using 3-nitrophenylacetic acid t-butyl ester as a starting material and also using 1,3-dibromopropane (1 eq.) as a reagent, the same procedures of Examples 1a and 1b gave 1-(3-nitrophenyl)cyclobutanecarboxylic acid.

Sources & evidence

ORD record
ord-f429b1ec4d374a1d90092abaebffc67e
Source dataset
uspto-grants-2003_03
Patent number
US06534546B1

Reaction notes

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