Triethoxy(3-isocyanatopropyl)silane → HCID 15484073, compound

HRID 1862075Notes

Reaction equation

HRID 1862075 reaction equation
[CH3:1][C:2]1([CH3:36])[CH2:29][NH:28][CH2:27][CH2:26][NH:25][CH2:24][C:23]([CH3:31])([CH3:30])[CH2:22][NH:21][CH2:20][CH2:19][NH:18][CH2:17][C:16]([CH3:33])([CH3:32])[CH2:15][NH:14][CH2:13][CH2:12][NH:11][CH2:10][C:9]([CH3:35])([CH3:34])[CH2:8][NH:7][CH2:6][CH2:5][NH:4][CH2:3]1.[N:37]([CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:47][CH2:48][CH3:49])[O:44][CH2:45][CH3:46])=[C:38]=[O:39]>O1CCCC1>[CH3:1][C:2]1([CH3:36])[CH2:3][N:4]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:5][CH2:6][N:7]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:8][C:9]([CH3:35])([CH3:34])[CH2:10][N:11]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:12][CH2:13][N:14]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:15][C:16]([CH3:33])([CH3:32])[CH2:17][N:18]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:19][CH2:20][N:21]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:22][C:23]([CH3:31])([CH3:30])[CH2:24][N:25]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:50][CH2:51][CH3:52])([O:44][CH2:45][CH3:46])[O:47][CH2:48][CH3:49])=[O:39])[CH2:26][CH2:27][N:28]([C:38]([NH:37][CH2:40][CH2:41][CH2:42][Si:43]([O:44][CH2:45][CH3:46])([O:50][CH2:51][CH3:52])[O:47][CH2:48][CH3:49])=[O:39])[CH2:29]1

Participants

4

Reactant 2

HCID 90613Triethoxy(3-isocyanatopropyl)silaneHCID 15424175HCID 15424175, compound

Product 1

HCID 15484073HCID 15484073, compoundYield 58.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

0.69 g (1.35 mmol) of 6,6,13,13,20,20,27,27-octamethyl-1,4,8,11,15,18,22,25-octaazacyclooctacosane is dissolved in 20 cm3 of anhydrous tetrahydrofuran (THF) in a 200 cm3 Schlenk tube. 3.2 g (12.9 mmol) of (3-isocyanatopropyl) triethoxysilane are rapidly added. The reaction mixture is stirred at room temperature for 12 hours. After evaporating the solvent, the solid obtained is washed twice with 50 cm3 of anhydrous pentahe. 1.97 g of the expected compound are obtained in the form of a white powder.

Workup

  1. customAfter evaporating the solvent
  2. customthe solid obtained
  3. washis washed twice with 50 cm3 of anhydrous pentahe

Sources & evidence

ORD record
ord-30e4d632bc3d4e03b22338ad24bfb61e
Source dataset
uspto-grants-2003_03
Patent number
US06534649B1

Reaction notes

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