5-Benzyloxy-4-{1-(methoxycarbonyl)ethoxy}pyrimidine → 5-Hydroxy-4-{1-(methoxycarbonyl)ethoxy}pyrimidine

Participants

Reaction Steps

A mixture of 5-benzyloxy-4-{1-(methoxycarbonyl)ethoxy}pyrimidine, 10% palladium/carbon and ethyl acetate is stirred for 3 hours at room temperature under hydrogen atmosphere. The reaction system is purged with nitrogen, then, the reaction solution is filtrated through Celite, and the filtrate is concentrated to obtain 5-hydroxy-4-{1-(methoxycarbonyl)ethoxy}pyrimidine.

Provenance & Evidence