Sulfuric acid magnesium salt (1:1) → D-Arabitol

HRID 1862564Notes

Reaction equation

HRID 1862564 reaction equation
[O:1]=[CH:2][C@@H:3]([C@H:5]([C@@H:7]([C@@H:9](CO)[OH:10])[OH:8])[OH:6])[OH:4].OP([O-])(O)=O.[K+].[O-]S([O-])(=O)=O.[Mg+2]>>[CH2:9]([OH:10])[C@@H:7]([OH:8])[CH:5]([OH:6])[C@H:3]([OH:4])[CH2:2][OH:1]

Participants

4

Reactant 3

HCID 24083Sulfuric acid magnesium salt (1:1)HCID 107526(2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanalHCID 516951Monobasic potassium phosphate

Product 1

HCID 94154D-ArabitolYield 36%

Conditions

Temperature
120 °C

Procedure

A culture medium (pH=6.0) containing 10% of D-glucose, 0.5% of peptone, 0.1% of KH2PO4, 0.05% of MgSO4, and 0.2% of yeast extract was sterilized by heating at 120° C. for 15 minutes. After sterilization, 2%(w/v) of CaCO3 sterilized separately was added thereto, in order to prevent the decrease of the medium pH during the progress of culturing. Onto the culture medium, the above-mentioned culture solution was inoculated in an amount of 10%(v/v), and was cultured at 30° C. On the third day of the culturing, D-arabitol had been formed at a concentration of 3.6 g/dl (36% yield based on the D-glucose).

Workup

  1. extractionextract
  2. additionAfter sterilization, 2%(w/v) of CaCO3 sterilized separately was added
  3. customwas cultured at 30° C

Sources & evidence

ORD record
ord-a68d5fa5fd7346fea4fda7237d6e984b
Source dataset
uspto-grants-2003_03
Patent number
US06538133B1

Reaction notes

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